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Future research should prioritize RCTs, pharmacokinetic studies, and long-term safety assessments to establish evidence-based guidelines for their use in health and disease management

We conclude that the acidic residues within Axin LIRup are essential for its binding to LRP6 while the RKR residues within LIR are at best contributory

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The feasibility of intranasal drug delivery is limited in the context of a patient with a skull fracture impacting the nasal cavity or cribriform plate, a history of coagulopathy disorder or friable (crumbly) nasal mucosa

There are several studies addressing the administration of BHB, AcAc, or acetone in diverse models of epilepsy, either chemically or genetically induced